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Laboratory Tests. The correct dosage and schedule for maintaining the serum uric acid within the normal range is best determined by using the serum uric acid as an index.
Drug/Laboratory Test Interactions. ZYLOPRIM (allopurinol) is not known to alter the accuracy of laboratory tests.
Avoid drinking alcohol while taking allopurinol.as it may make your condition worse. Allopurinol may impair your thinking or reaction time.so you should be especially careful when driving or performing any activity that requires you to be alert.
The reports that the concomitant use of ZYLOPRIM (allopurinol) and thi-azide diuretics may contribute to the enhancement of allopuri-nol toxicity in some patients have been reviewed in an attempt to establish a cause-and-effect relationship and a mechanism of causation. Review of these case reports indicates that the patients were mainly receiving thiazide diuretics for order zyloprim side and that tests to rule out decreased renal function secondary to hypertensive nephropathy were not often performed. In those patients in whom renal insufficiency was documented.however.the recommendation to lower the dose of ZYLOPRIM (allopurinol) was not followed. Although a causal mechanism and a cause-and-effect relationship have not been established.current evidence suggests that renal function should be monitored in patients on thi-azide diuretics and ZYLOPRIM (allopurinol) even in the absence of renal failure.and order zyloprim side levels should be even more conservatively adjusted in those patients on such combined therapy if diminished renal function is detected.
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