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Smooth muscle prokinetic agents.for example.cisapride and metoclopramide.have limited clinical application in the treatment of canine idiopathic megaesophagus. Cisaprideand metoclopramide stimulate distal esophageal peristalsis in those animal species (e.g..cat.human being.guinea pig) in which the distal esophageal muscularis is composed of smooth muscle. The domestic dog has evolved with a purely striated muscle esophageal muscularis.which has a different regulation and therapeutic responsiveness. Bethanechol stimulates esophageal propagating contractions in some dogs affected with idiopathic megaesophagus and is therefore a more appropriate prokinetic agent for the therapy of this disorder.

Ranitidine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away.

For people with gastric cancer. This drug reduces the amount of acid in your stomach. This can help improve the symptoms of your gastrointestinal condition. However.if your symptoms are caused by a cancerous gastric tumor.you may still have the tumor. This drug does not treat cancer.

That said.this drug should only be used in pregnancy if clearly needed. Call your doctor right away if you become pregnant while taking this drug.

Ranitidine belongs to a class of drugs called histamine receptor antagonists. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

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do not take this medicine with any of the following medications -dofetilide -gatifloxacin -certain contrast medicines given before x-rays, ct scans, mri, or other procedures this medicine may also interact with the following medications -acetazolamide -atorvastatin -certain antiviral medicines for hiv or hepatitis -cimetidine -crizotinib -digoxin -diuretics -female hormones, like estrogens or progestins and birth control pills -gemfibrozil -glycopyrrolate -insulin -isoniazid -ketoconazole -lamotrigine -medicines for blood pressure, heart disease, irregular heart beat -memantine -methazolamide -midazolam -midodrine -morphine -niacin -phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine -phenytoin -procainamide -propantheline -quinidine -quinine -ranitidine -ranolazine -rifampin -steroid medicines like prednisone or cortisone -thyroid hormones -topiramate -trimethoprim -trospium -vancomycin -vandetanib -zonisamide.

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