However it does not appear that colchicine is fda-approved for this indication.
Information about Colchicine.
The concomitant use of colchicine capsules and CYP3A4 inhibitorse.gclarithromycinketoconazolegrapefruit juiceerythromycinverapamiletcshould be avoided due to the potential for serious and life-threatening toxicitySee WARNINGS AND PRECAUTIONS and CLINICAL PHARMACOLOGY
Dose reduction or alternatives should be considered for the prophylaxis of gout flares in patients with severe hepatic impairment.
The concomitant use of colchicine capsules and inhibitors of P-glycoproteine.gclarithromycinketoconazolecyclosporineetcshould be avoided due to the potential for serious and life-threatening toxicitySee WARNINGSAND PRECAUTIONS and CLINICAL PHARMACOLOGY
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solomon, md, published a letter in the nejm berating the fda for the negative impact that patients with gout and familial mediterranean fever would suffer as a result of this policy as applied to colchicine.
