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Although bupropion is not metabolized by cytochrome p450iid6 cyp2d6 , there is the potential for drug-drug interactions when bupropion is co-administered with drugs metabolized by this isoenzyme see precautions drug interactions .

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Bupropion oral tablet can interact with other medicationsvitaminsor herbs you may be takingAn interaction is when a substance changes the way a drug worksThis can be harmful or prevent the drug from working well.

Jay WMarksMDis a board-certified internist and gastroenterologistHe graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

You should not change your dose or stop using bupropion suddenlyunless you have a seizure while taking this medicineStopping suddenly can cause unpleasant withdrawal symptoms.

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the percentage of patients reporting 50 or more decrease in depressive symptoms did not differ between groups, but depressive symptoms improved more with bupropion sr than with placebo.

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