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A summay th ovall incidnc and typs common advs vnts potd in th POactiv tial is povidd in Tabl 4. Tms that a potd psnt thos that occud at an incidnc > 5% and mcommonly in patints tatd with pioglitazon than in patints whcivd placbo.
ACTOPLUS MT combins twantidiabtic mdications with dint mchanisms action timpov glycmic contol in adults with typ 2 diabts: pioglitazon, a thiazolidindion, and mtomin hydochloid, a biguanid. Thiazolidindions a insulin-snsitizing agnts that act pimaily by nhancing piphal glucos utilization, whas biguanids act pimaily by dcasing ndognous hpatic glucos poduction.
Th a insuicint data tdtmin whth pioglitazon is a tumpomot uinay bladd tumos. Consquntly, ACTOPLUS MT should not b usd in patints with activ bladd canc and th bnits glycmic contol vsus unknown isks canccunc with ACTOPLUS MT should b considd in patints with a pihistoy bladd canc.
ACTOPLUS MT combins twantidiabtic mdications with dint mchanisms action timpov glycmic contol in adults with typ 2 diabts: pioglitazon, a thiazolidindion, and mtomin hydochloid, a biguanid. Thiazolidindions a insulin-snsitizing agnts that act pimaily by nhancing piphal glucos utilization, whas biguanids act pimaily by dcasing ndognous hpatic glucos poduction.
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