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Thiazide diuretics may increase serum calcium levels due to decreased excretionIf calcium supplements or Vitamin D must be prescribedserum calciumlevels should be monitored and the dose adjusted accordingly.
Chronic administration of NSAIDselective cyclooxygenase-2 inhibitorsacetylsalicylic acid3 g/day and non-selective NSAIDsmay reduce the antihypertensive and diuretic effect of ACE inhibitors and thiazide diureticsNSAID and ACE inhibitors may exert an additive effect on the increase in serum potassium and may result in a deterioration of renal functionThese effects are usually reversibleRarelyacute renal failure may occurespecially in patients with compromised renal function such as the elderly or dehydrated.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Before using this medicationtell your doctor or pharmacist your medical historyespecially ofhistory of an allergic reaction that included swelling of the face/lips/tongue/throatangioedemablood filtering proceduressuch as LDL apheresisdialysisdesensitizing treatment for bee/wasp sting allergygoutlupuskidney diseaseliver disease.
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