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Heart attack acute myocardial infarction is treated with three 5 mg injections administered 2 minutes apart followed by treatment with 50 mg oral metoprolol every 6 hours for 48 hours.

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Safety and effectiveness of TOPROL-XL have not been established in patients.

Take this medication by mouth as directed by your doctorusually once dailySome brands of this medicationthose containing metoprolol tartratemay be better absorbed when you take them with or right after a mealOther brandsthose containing metoprolol succinatemay be taken with or without foodFollow your doctor’s directions for your brandand take it the same way at the same time each day.

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instruct patients not to interrupt or discontinue metoprolol succinate extended release hydrochlorothiazide without consulting a healthcare provider.

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