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The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongationBefore using fluoxetinetell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death
When treating a pregnant woman with fluoxetinethe physician should carefully consider both the potential risks of taking an SSRIalong with the established benefits of treating depression with an antidepressantThe decision can only be made on a case by case basis.
Older adults may be more sensitive to the side effects of this drugespecially bleeding and QT prolongationsee aboveOlder adults may also be more likely to develop low sodium in the bloodespecially if they are takingwater pillsdiuretics
There are no clinical studies establishing the benefit of the combined use of ECT and fluoxetineThere have been rare reports of prolonged seizures in patients on fluoxetine receiving ECT treatment.
Tell the doctor right away if you notice worsening depression/other psychiatric conditionsunusual behavior changesincluding possible suicidal thoughts/attemptsor other mental/mood changesincluding new/worsening anxietypanic attackstrouble sleepingirritabilityhostile/angry feelingsimpulsive actionssevere restlessnessvery rapid speechBe especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.
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