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Information about Lisinopril.
This is not a list of all drugs or health problems that interact with this medicinelisinopril tablets
If you need surgerytell the surgeon ahead of time that you are using lisinopril.
If you miss a dose of lisinopriltake it as soon as you rememberIf you don’t remember until the following dayskip the missed doseDo not take a double dose to make up for a forgotten one.
USBOXED WARNINGS FETAL TOXICITYAngiotensin converting enzymeACEinhibitor use during pregnancy can cause morbidity and death to the developing fetusWhen used during the second and third trimestersACE inhibitors have been associated with fetal and neonatal injuryincluding hypotensionneonatal skull hypoplasiaanuriareversible or irreversible renal failureand deathOligohydramnios has also been reportedpresumably resulting from decreased fetal renal functionoligohydramnios in this setting has been associated with fetal limb contracturescraniofacial deformationand hypoplastic lung developmentExposure to ACE inhibitors during the first trimester of pregnancy has been associated with prematurityintrauterine growth retardationpatent ductus arteriosusother structural cardiac malformationsand neurological malformationsWhen pregnancy is detectedACE inhibitors should be discontinued as soon as possibleIf no alternative to ACE inhibitor therapy is availablepatients should be made aware of the risks to their fetuses and the intra-amniotic environment should be evaluated by serial ultrasound examinationsIf oligohydramnios developsthis drug should be discontinued unless it is considered lifesaving for the motherDepending on the week of pregnancycontraction stress testinga nonstress testor biophysical profiling may be appropriateOligohydramnios may not show until after the fetus has suffered irreversible injury.
Patient advice This drug may be taken with or without foodbut should be taken at the same time each dayThis drug may impair your ability to drive or operate machinery.
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