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Verapamil HCI is an almost whitecrystalline powderpractically free of odorwith a bitter taste.

Antihypertensive AgentsVerapamil administered concomitantly with oral antihypertensive agentse.gvasodilatorsangiotensin-converting enzyme inhibitorsdiureticsbeta blockerswill usually have an additive effect on lowering blood pressurePatients receiving these combinations should be appropriately monitoredConcomitant use of agents that attenuate alpha-adrenergic function with verapamil may result in a reduction in blood pressure that is excessive in some patientsSuch an effect was observed in one study following the concomitant administration of verapamil and prazosin.

Beta BlockersConcomitant therapy with beta-adrenergic blockers and verapamil may result in additive negative effects on heart rateatrioventricular conductionand/or cardiac contractilityThe combination of sustained-release verapamil and beta-adrenergic blocking agents has not been studiedHoweverthere have been reports of excessive bradycardia and AV blockincluding complete heart blockwhen the combination has been used for the treatment of hypertensionFor hypertensive patientsthe risks of combined therapy may outweigh the potential benefitsThe combination should be used only with caution and close monitoring.

Use this medication regularly to get the most benefit from itTo help you remembertake it at the same times each day.

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