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Information about Imuran.

Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.

Benefit versus risk must be weighed carefully before use of IMURAN in patients of reproductive potentialThere are no adequate and well-controlled studies in pregnant womenIf this drug is used during pregnancy or if the patient becomes pregnant while taking this drugthe patient should be apprised of the potential hazard to the fetusWomen of childbearing age should be advised to avoid becoming pregnant.

If you think there has been an overdosecall your poison control center or get medical care right awayBe ready to tell or show what was takenhow muchand when it happened.

As there is in vitro evidence that aminosalicyclate derivatives(egolsalazinemesalazine or sulphasalazineinhibit the TPMT enzymethey should be administered with caution to patients receiving concurrent Imuran therapysee 4.4 Special Warning and Special Precautions for Use

It has been suggested that the toxicity of Imuran may be enhanced in the presence of renal insufficiencybut controlled studies have not supported this suggestionNeverthelessit is recommended that the dosages used should be at the lower end of the normal range and that haematological response should be carefully monitoredDosage should be further reduced if haematological toxicity occurs.

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htm imuran official prescribing information for healthcare professionals.