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What is a package insertA package insert is required by the FDA and contains a summary of the essential scientific information needed for the safe and effective use of the drug for healthcare providers and consumersA package insert typically includes information regarding specific indicationsadministration schedulesdosingside effectscontraindicationsresults from some clinical trialschemical structurepharmacokinetics and metabolism of the specific drugBy carefully reviewing the package insertyou will get the most complete and current information about how to safely use this drugIf you do not have the package insert for the drug you are usingyour pharmacist or physician may be able to provide you with a copy.

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The adverse effects of corticosteroids in pediatric patients are similar to those in adultssee ADVERSE REACTIONSLike adultspediatric patients should be carefully observed with frequent measurements of blood pressureweightheightintraocular pressureand clinical evaluation for the presence of infectionpsychosocial disturbancesthromboembolismpeptic ulcerscataractsand osteoporosisPediatric patients who are treated with corticosteroids by any routeincluding systemically administered corticosteroidsmay experience a decrease in their growth velocityThis negative impact of corticosteroids on growth has been observed at low systemic doses and in the absence of laboratory evidence of hypothalamic-pituitary-adrenalHPAaxis suppressioni.ecosyntropin stimulation and basal cortisol plasma levelsGrowth velocity may therefore be a more sensitive indicator of systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis functionThe linear growth of pediatric patients treated with corticosteroids should be monitoredand the potential growth effects of prolonged treatment should be weighed against clinical benefits obtained and the availability of treatment alternativesIn order to minimize the potential growth effects of corticosteroidspediatric patients should be titrated to the lowest effective dose.

Increased dosage of rapidly acting corticosteroids is indicated in patients on corticosteroid therapy subjected to any unusual stress beforeduringand after the stressful situation.

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